Cyclin C (phospho Ser275) rabbit pAb
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
P24863
Swiss Prot
P24863
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Cyclin C around the phosphorylation site of Ser275. AA range:234-283
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
33-37kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
33-37kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
CCNC; Cyclin-C; SRB11 homolog; hSRB11
Gene ID (Human)
892
Available Sizes
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