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VAMP-4 rabbit pAb

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008]

Synonyms

VAMP4; Vesicle-associated membrane protein 4; VAMP-4

Gene ID

8674

UniProt

O75379

Cellular Locus

Golgi apparatus, trans-Golgi network membrane ; Single-pass type IV membrane protein. Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human VAMP4. AA range:1-50

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IF, ELISA

Validated Applications

IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7853-1.pdf

Subcellular Location

Golgi apparatus, trans-Golgi network membrane ; Single-pass type IV membrane protein . Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG) . Not found on the mature secretory organelles.

Other Product Names

VAMP4; Vesicle-associated membrane protein 4; VAMP-4

Gene ID (Human)

8674

SwissProt (Human)

O75379

Available Sizes

Curated Selection

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