FMIP rabbit pAb
Function: May be involved in the differentiation of granulocytes and adipocytes. PTM: Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the THOC5 family. subcellular location: Shuttles between nucleus and cytoplasm. subunit: Interacts with phosphorylated CSF1R. tissue specificity: Ubiquitously expressed.
Product Specifications
Background
Synonyms
Gene ID
8563
UniProt
Q13769
Cellular Locus
Nucleus. Cytoplasm. Shuttles between nucleus and cytoplasm..
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human THOC5. AA range:561-610
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
78kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7821-1.pdf
Observed Molecular Weight
78 kD
Subcellular Location
Nucleus . Cytoplasm . Shuttles between nucleus and cytoplasm. .
Other Product Names
Gene ID (Human)
8563
SwissProt (Human)
Q13769
Available Sizes
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