IKKγ (phospho Ser85) rabbit pAb
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016],
Product Specifications
Background
UniProt
Q9Y6K9
Swiss Prot
Q9Y6K9
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human IKK-gamma around the phosphorylation site of Ser85. AA range:51-100
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
48kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
48kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress. .
Other Product Names
Gene ID (Human)
8517
Available Sizes
Frequently Asked Questions
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