NFATc2IP rabbit pAb

Function: Plays a role in the inducible expression of Cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production. PTM: Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented Cytokine production. similarity: Contains 1 ubiquitin-like domain. subcellular location: TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. subunit: Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.

Product Specifications

Background

Function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production., PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production., similarity:Contains 1 ubiquitin-like domain., subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus., subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.

UniProt

Q8NCF5

Swiss Prot

Q8NCF5

Reactivity

Human; Rat; Mouse; ; Fish

Immunogen

The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Molecular Weight

48kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

48kD

Fragment

IgG

Subcellular Location

Nucleus . Cytoplasm . TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. .

Other Product Names

NFATC2IP; NIP45; NFATC2-interacting protein; 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; Nuclear factor of activated T-cells; cytoplasmic 2-interacting protein