Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

CaSR rabbit pAb

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH) -producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008]

Synonyms

CASR; GPRC2A; PCAR1; Extracellular calcium-sensing receptor; CaSR; Parathyroid cell calcium-sensing receptor; PCaR1

Gene ID

846

UniProt

P41180

Cellular Locus

Cell membrane ; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Calcium Sensing Receptor. AA range:854-903

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight

140kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7764-1.pdf

Observed Molecular Weight

140 kD

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

Other Product Names

CASR; GPRC2A; PCAR1; Extracellular calcium-sensing receptor; CaSR; Parathyroid cell calcium-sensing receptor; PCaR1

Gene ID (Human)

846

SwissProt (Human)

P41180

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

LIR-7 Polyclonal Antibody
UB-GEN-13818 100 ul

LIR-7 Polyclonal Antibody

Ask
View Details
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MMS21 Polyclonal Antibody
MBS9002063 Inquire

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) MMS21 Polyclonal Antibody

Ask
View Details
Mouse Monoclonal IgG Antibody (SPM556) [mFluor Violet 500 SE]
NBP2-34428MFV500 0.1 mL

Mouse Monoclonal IgG Antibody (SPM556) [mFluor Violet 500 SE]

Ask
View Details
FGF17 (NM_003867) Human Recombinant Protein
TP720979L 500 µg

FGF17 (NM_003867) Human Recombinant Protein

Ask
View Details