ATRIP (phospho Ser68) rabbit pAb
This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012],
Product Specifications
Background
Synonyms
ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein
Gene ID
84126
UniProt
Q8WXE1
Cellular Locus
Nucleus. Redistributes to discrete nuclear foci upon DNA damage.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ATRIP around the phosphorylation site of Ser68. AA range:34-83
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
80kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7732-1.pdf
Observed Molecular Weight
80 kD
Subcellular Location
Nucleus . Redistributes to discrete nuclear foci upon DNA damage.
Other Product Names
ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein
Gene ID (Human)
84126
SwissProt (Human)
Q8WXE1
Available Sizes
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