Rab11-FIP1 rabbit pAb

This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013],

Product Specifications

Background

UniProt

Q6WKZ4

Swiss Prot

Q6WKZ4

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from Rab11-FIP1 . at AA range: 70-150

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Recycling endosome . Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC) .; [Isoform 2]: Cytoplasmic vesicle, phagosome membrane. Membrane-bound (isoform 2) . Colocalizes with Rab11A at phagosomes (isoform 2) .