Microcephalin rabbit pAb
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010],
Product Specifications
Background
UniProt
Q8NEM0
Swiss Prot
Q8NEM0
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MCPH1. AA range:91-140
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
93kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
93kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
Other Product Names
MCPH1; Microcephalin
Gene ID (Human)
79648
Available Sizes
Frequently Asked Questions
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