SH3TC2 rabbit pAb
This gene encodes a protein with two N-terminal Src homology 3 (SH3) domains and 10 tetratricopeptide repeat (TPR) motifs, and is a member of a small gene family. The gene product has been proposed to be an adapter or docking molecule. Mutations in this gene result in autosomal recessive Charcot-Marie-Tooth disease type 4C, a childhood-onset neurodegenerative disease characterized by demyelination of motor and sensory neurons. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q8TF17
Swiss Prot
Q8TF17
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human SH3TC2. AA range:390-430
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Plasma membrane, cytoplasmic vesicle, recycling endosome
Other Product Names
SH3TC2; KIAA1985; PP12494; SH3 domain and tetratricopeptide repeat-containing protein 2
Gene ID (Human)
79628
Available Sizes
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