Zic1/2/3 rabbit pAb

This gene encodes a member of the ZIC family of C2H2-type Zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding Zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008]

UniProt

Q15915/O95409/O60481

Swiss Prot

Q15915/O95409/O60481

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human ZIC1/2/3. AA range:316-365

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

51kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

51kD

Fragment

IgG

Subcellular Location

Nucleus. Cytoplasm . Localizes in the cytoplasm in presence of MDFIC overexpression. .

Other Product Names

ZIC1; ZIC; ZNF201; Zinc finger protein ZIC 1; Zinc finger protein 201; Zinc finger protein of the cerebellum 1; ZIC2; Zinc finger protein ZIC 2; Zinc finger protein of the cerebellum 2; ZIC3; ZNF203; Zinc finger protein ZIC 3; Zinc finger p