14-3-3 β/ζ (phospho Ser184/186) rabbit pAb
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008],
Product Specifications
Background
Synonyms
Gene ID
7534/7529
UniProt
P63104/P31946
Cellular Locus
Cytoplasm. Melanosome. Located to stage I to stage IV melanosomes.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
28kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7526-1.pdf
Observed Molecular Weight
28 kD
Subcellular Location
Cytoplasm . Melanosome . Located to stage I to stage IV melanosomes.
Other Product Names
Gene ID (Human)
7534/7529
SwissProt (Human)
P63104/P31946
Available Sizes
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