Wee 1 (phospho Ser53) rabbit pAb
WEE1 G2 checkpoint kinase (WEE1) Homo sapiens This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
WEE1; Wee1-like protein kinase; WEE1hu; Wee1A kinase
Gene ID
7465
UniProt
P30291
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human WEE1 around the phosphorylation site of Ser53. AA range:19-68
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IHC, IF, ELISA
Validated Applications
IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7516-1.pdf
Subcellular Location
Nucleus.
Other Product Names
WEE1; Wee1-like protein kinase; WEE1hu; Wee1A kinase
Gene ID (Human)
7465
SwissProt (Human)
P30291
Available Sizes
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