Ezrin (phospho Tyr353) rabbit pAb
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81
UniProt
P15311
Swiss Prot
P15311
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Ezrin around the phosphorylation site of Tyr353. AA range:321-370
Target
Ezrin
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
69kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
69kD
Fragment
IgG
Subcellular Location
Other Product Names
EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81
Gene ID (Human)
7430
Available Sizes
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PA2G4 (38kDa, AA672939, Cell Cycle Protein p38 2G4 Homolog, Cell Cycle Protein p38-2G4 Homolog, ErbB-3 Binding Protein 1, ErbB3 Binding Protein 1, ErbB3-Binding Protein 1, ErbB3-Binding Protein Ebp1, hG4 1, hG4-1, IRES-specific Cellular trans-Acting Factor 45kD, MGC81621, MGC94070, Mpp1, p38 2G4, PA2G4, PA2G4_HUMAN, Plfap, Proliferation Associated 2G4, Proliferation Associated 2G4, 38-KD, Proliferation-Associated 2G4, 38kDa, Proliferation-Associated 2G4, a, Proliferation-Associated Protein 1, Proliferation-Associated Protein 2G4, Protein p38-2G4, si:dz150i12.2, wu:fb19b11, wu:ft56d05, zgc:86732, ) discontinued
PA2G4 (38kDa, AA672939, Cell Cycle Protein p38 2G4 Homolog, Cell Cycle Protein p38-2G4 Homolog, ErbB-3 Binding Protein 1, ErbB3 Binding Protein 1, ErbB3-Binding Protein 1, ErbB3-Binding Protein Ebp1, hG4 1, hG4-1, IRES-specific Cellular trans-Acting Factor 45kD, MGC81621, MGC94070, Mpp1, p38 2G4, PA2G4, PA2G4_HUMAN, Plfap, Proliferation Associated 2G4, Proliferation Associated 2G4, 38-KD, Proliferation-Associated 2G4, 38kDa, Proliferation-Associated 2G4, a, Proliferation-Associated Protein 1, Proliferation-Associated Protein 2G4, Protein p38-2G4, si:dz150i12.2, wu:fb19b11, wu:ft56d05, zgc:86732, ) discontinued
