Ezrin (phospho Tyr353) rabbit pAb
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81
Gene ID
7430
UniProt
P15311
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Ezrin around the phosphorylation site of Tyr353. AA range:321-370
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
69kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7501-1.pdf
Observed Molecular Weight
69 kD
Subcellular Location
Other Product Names
EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81
Gene ID (Human)
7430
SwissProt (Human)
P15311
Available Sizes
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