MRP-L49 rabbit pAb
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p. [provided by RefSeq, May 2011],
Product Specifications
Background
Synonyms
MRPL49; C11orf4; NOF1; OK/SW-cl.67; 39S ribosomal protein L49; mitochondrial; L49mt; MRP-L49; Neighbor of FAU; NOF; Protein NOF1
Gene ID
740
UniProt
Q13405
Cellular Locus
Mitochondrion.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from MRP-L49 . at AA range: 10-90
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
19kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7479-1.pdf
Observed Molecular Weight
19 kD
Subcellular Location
Mitochondrion .
Other Product Names
MRPL49; C11orf4; NOF1; OK/SW-cl.67; 39S ribosomal protein L49; mitochondrial; L49mt; MRP-L49; Neighbor of FAU; NOF; Protein NOF1
Gene ID (Human)
740
SwissProt (Human)
Q13405
Available Sizes
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