Txk rabbit pAb

Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily. similarity: Contains 1 protein kinase domain. similarity: Contains 1 SH2 domain. similarity: Contains 1 SH3 domain. tissue specificity: Expressed in T-cells and some myeloid cell lines.

Product Specifications

Background

Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate., similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 1 SH2 domain., similarity:Contains 1 SH3 domain., tissue specificity:Expressed in T-cells and some myeloid cell lines.

UniProt

P42681

Swiss Prot

P42681

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Txk.

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cytoplasm . Nucleus . Cell membrane ; Peripheral membrane protein . Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation. Translocates into the nucleus and enhances IFN-gamma gene transcription in T-cells.