FX rabbit pAb

Tissue specific transplantation antigen P35B is a NADP (H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Tissue specific transplantation antigen P35B is a NADP (H) -binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008]

Product Name Alternative

TSTA3; SDR4E1; GDP-L-fucose synthase; GDP-4-keto-6-deoxy-D-mannose-3; 5-epimerase-4-reductase; Protein FX; Red cell NADP (H) -binding protein; Short-chain dehydrogenase/reductase family 4E member 1

UniProt

Q13630

Swiss Prot

Q13630

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human TSTA3. AA range:221-270

Target

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

40kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

40kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytosol, extracellular exosome

Other Product Names

TSTA3; SDR4E1; GDP-L-fucose synthase; GDP-4-keto-6-deoxy-D-mannose-3; 5-epimerase-4-reductase; Protein FX; Red cell NADP (H) -binding protein; Short-chain dehydrogenase/reductase family 4E member 1