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TRH-R1 rabbit pAb

This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011],

Product Specifications

Background

This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH) . Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011]

Synonyms

TRHR; Thyrotropin-releasing hormone receptor; TRH-R; Thyroliberin receptor

Gene ID

7201

UniProt

P34981

Cellular Locus

Cell membrane ; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat,Monkey

Reactivity

Human; Mouse; Rat; Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human TRHR. AA range:195-244

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IF, ELISA

Validated Applications

WB,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

50kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7446-1.pdf

Observed Molecular Weight

50 kD

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

Other Product Names

TRHR; Thyrotropin-releasing hormone receptor; TRH-R; Thyroliberin receptor

Gene ID (Human)

7201

SwissProt (Human)

P34981

Available Sizes

Curated Selection

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