TPH1 (phospho Ser58) rabbit pAb
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others. [provided by RefSeq, Apr 2009],
Product Specifications
Background
UniProt
P17752
Swiss Prot
P17752
Reactivity
Human; Mouse; Rat
Immunogen
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
51kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
51kD
Fragment
IgG
Subcellular Location
Cytosol, neuron projection
Other Product Names
TPH1; TPH; TPRH; TRPH; Tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1
Gene ID (Human)
7166
Available Sizes
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