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Thymidine Kinase rabbit pAb

Catalytic activity: ATP + thymidine = ADP + thymidine 5'-phosphate. miscellaneous: Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells. PTM: Phosphorylated on Ser-13 in mitosis. similarity: Belongs to the thymidine kinase family.

Product Specifications

Background

Catalytic activity:ATP + thymidine = ADP + thymidine 5'-phosphate., miscellaneous:Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells., PTM:Phosphorylated on Ser-13 in mitosis., similarity:Belongs to the thymidine kinase family.

Synonyms

TK1; Thymidine kinase; cytosolic

Gene ID

7083

UniProt

P04183

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Monkey

Reactivity

Human; Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human KITH. AA range:161-210

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC

Validated Applications

WB,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300

Molecular Weight

25kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7397-1.pdf

Observed Molecular Weight

25 kD

Subcellular Location

Cytoplasm.

Other Product Names

TK1; Thymidine kinase; cytosolic

Gene ID (Human)

7083

SwissProt (Human)

P04183

Available Sizes

Curated Selection

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