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Thymidine Kinase (phospho Ser13) rabbit pAb

Catalytic activity: ATP + thymidine = ADP + thymidine 5'-phosphate. miscellaneous: Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells. PTM: Phosphorylated on Ser-13 in mitosis. similarity: Belongs to the thymidine kinase family.

Product Specifications

Background

Catalytic activity:ATP + thymidine = ADP + thymidine 5'-phosphate., miscellaneous:Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells., PTM:Phosphorylated on Ser-13 in mitosis., similarity:Belongs to the thymidine kinase family.

Synonyms

TK1; Thymidine kinase; cytosolic

Gene ID

7083

UniProt

P04183

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat,Pig

Reactivity

Human; Mouse; Rat; Pig (Test by out customer)

Immunogen

The antiserum was produced against synthesized peptide derived from human TK around the phosphorylation site of Ser13. AA range:1-50

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight

25kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7396-1.pdf

Observed Molecular Weight

25 kD

Subcellular Location

Cytoplasm.

Other Product Names

TK1; Thymidine kinase; cytosolic

Gene ID (Human)

7083

SwissProt (Human)

P04183

Available Sizes

Curated Selection

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