Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

TGFβ RII (phospho Ser225) rabbit pAb

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

UniProt

P37173

Swiss Prot

P37173

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human TGF beta Receptor II around the phosphorylation site of Ser225/250. AA range:191-240

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 , Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

75kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

75kD

Fragment

IgG

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Membrane raft .; [Isoform 3]: Secreted .

Other Product Names

TGFBR2; TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II

Gene ID (Human)

7048

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Pold2 Mouse shRNA Plasmid (Locus ID 18972)
TR510548 1 Kit

Pold2 Mouse shRNA Plasmid (Locus ID 18972)

Ask
View Details
Recombinant Influenza B virus Non-structural protein 1 (NS)
CSB-YP319433IJU-01 20 µg

Recombinant Influenza B virus Non-structural protein 1 (NS)

Ask
View Details
Recombinant Influenza B virus Non-structural protein 1 (NS)
CSB-YP319433IJU-02 100 µg

Recombinant Influenza B virus Non-structural protein 1 (NS)

Ask
View Details
Recombinant Influenza B virus Non-structural protein 1 (NS)
CSB-YP319433IJU-03 1 mg

Recombinant Influenza B virus Non-structural protein 1 (NS)

Ask
View Details
TSN, ID (TSN, Translin, Component 3 of promoter of RISC) (MaxLight 490) discontinued
043369-ML490 100 µL

TSN, ID (TSN, Translin, Component 3 of promoter of RISC) (MaxLight 490) discontinued

Ask
View Details
Human Prepro-Insulin Monoclonal Antibody
E55A11330 100 µL

Human Prepro-Insulin Monoclonal Antibody

Ask
View Details