pJAK2(1001–1013)
Product Specifications
UNSPSC Description
pJAK2(1001-1013) is a SOCS1/3 antagonist. pJAK2(1001–1013) plays a positive role in antiviral immune response by inhibiting the negative regulatory effect of SOCS proteins and enhancing the JAK/STAT signaling pathway[1]
Target Antigen
JAK
Type
Peptides
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pjak2-1001-1013.html
Purity
99.80
Solubility
DMSO : 1.89 mg/mL (ultrasonic;adjust pH to 2 with 1 M HCL)
Smiles
O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N2[C@H](C(O)=O)CCC2)=O)=O)=O)=O)=O)[C@@H](NC([C@H](CCC(O)=O)NC([C@H](CCCCN)NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H]3N(C([C@H](CC(C)C)N)=O)CCC3)=O)=O)=O)=O)=O)CC4=CC=C(OP(O)(O)=O)C=C4
Molecular Weight
1716.82
References & Citations
[1]Ahmed C M, et al. A SOCS1/3 antagonist peptide protects mice against lethal infection with influenza A virus[J]. Frontiers in immunology, 2015, 6: 574.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10373/pJAK2-1001-1013-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10373/pJAK2-1001-1013-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1259928-08-9
Available Sizes
Curated Selection
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