TACC1 rabbit pAb

This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009],

Product Specifications

Background

Product Name Alternative

TACC1; KIAA1103; Transforming acidic coiled-coil-containing protein 1; Gastric cancer antigen Ga55; Taxin-1

UniProt

O75410

Swiss Prot

O75410

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human TACC1. AA range:11-60

Target

TACC1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

87kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

87kD

Fragment

IgG

Subcellular Location

Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Midbody . Nucleus during interphase. Weakly concentrated at centrosomes during mitosis and colocalizes with AURKC at the midbody during cytokinesis. .; [Isoform 5]: Membrane ; Lipid-anchor .; [Isoform 10]: Cytoplasm .