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Syk rabbit pAb

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

Product Specifications

Background

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

UniProt

P43405

Swiss Prot

P43405

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from Syk . at AA range: 290-370

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Molecular Weight

72kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

72kD

Fragment

IgG

Subcellular Location

Cell membrane . Cytoplasm, cytosol .

Other Product Names

SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk

Gene ID (Human)

6850

Available Sizes

Curated Selection

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