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Syk rabbit pAb

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

Product Specifications

Background

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Synonyms

SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk

Gene ID

6850

UniProt

P43405

Cellular Locus

Cell membrane. Cytoplasm, cytosol.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from Syk . at AA range: 290-370

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA, IHC

Validated Applications

WB,ELISA,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Molecular Weight

72kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7323-1.pdf

Observed Molecular Weight

72 kD

Subcellular Location

Cell membrane . Cytoplasm, cytosol .

Other Product Names

SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk

Gene ID (Human)

6850

SwissProt (Human)

P43405

Available Sizes

Curated Selection

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