Bmx (phospho Tyr40) rabbit pAb
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3, 4, 5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],
Product Specifications
Background
Synonyms
Gene ID
660
UniProt
P51813
Cellular Locus
Cytoplasm. Localizes to the edges of spreading cells when complexed with BCAR1.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human ETK around the phosphorylation site of Tyr40. AA range:6-55
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Molecular Weight
78kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7241-1.pdf
Observed Molecular Weight
78 kD
Subcellular Location
Cytoplasm . Localizes to the edges of spreading cells when complexed with BCAR1.
Other Product Names
Gene ID (Human)
660
SwissProt (Human)
P51813
Available Sizes
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