Poacic acid

Poacic Acid is a plant-derived stilbenoid with an antifungal activity. Poacic Acid localizes to the yeast cell wall and disrupts the production and assembly of β-1,3-glucan in the fungal cell walls. Poacic Acid exhibits fungicidal activity to Saccharomyces cerevisiae and plasma membrane-compromised Candida albicans mutants[1].

Product Specifications

CAS Number

[160097-32-5]

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/poacic-acid.html

Purity

97.21

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC1=CC(/C=C/C(O)=O)=CC(/C=C/C2=CC(OC)=C(C=C2)O)=C1O

Molecular Formula

C19H18O6

Molecular Weight

342.34

References & Citations

[1]Yona A, et al. Poacic Acid, a Plant-Derived Stilbenoid, Augments Cell Wall Chitin Production, but Its Antifungal Activity Is Hindered by This Polysaccharide and by Fungal Essential Metals. Biochemistry. 2024 Apr 16;63 (8) :1051-1065.