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CYP3A43 rabbit pAb

Cytochrome P450 family 3 subfamily A member 43 (CYP3A43) Homo sapiens This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of Cytochrome P450 genes on chromosome 7q21. 1. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013],

Product Specifications

Background

Cytochrome P450 family 3 subfamily A member 43 (CYP3A43) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

UniProt

Q9HB55

Swiss Prot

Q9HB55

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human Cytochrome P450 3A43. AA range:231-280

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

57kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

57kD

Fragment

IgG

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Other Product Names

CYP3A43; Cytochrome P450 3A43

Gene ID (Human)

64816

Available Sizes

Curated Selection

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