POLR1E rabbit pAb

Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF. similarity: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family. subunit: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity). Interacts with PAF49/CD3EAP. Also binds UBTF/UBF.

Product Specifications

Background

Function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF., similarity:Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family., subunit:Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity) . Interacts with PAF49/CD3EAP. Also binds UBTF/UBF.

UniProt

Q9GZS1

Swiss Prot

Q9GZS1

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from the Internal region of human POLR1E.

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

49kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

49kD

Fragment

IgG

Subcellular Location

Nucleus, nucleolus .

Other Product Names

POLR1E; PAF53; PRAF1; DNA-directed RNA polymerase I subunit RPA49; RNA polymerase I subunit A49; DNA-directed RNA polymerase I subunit E; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53