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Sarcoglycan α rabbit pAb

Sarcoglycan alpha (SGCA) Homo sapiens This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],

Product Specifications

Background

Sarcoglycan alpha (SGCA) Homo sapiens This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Product Name Alternative

SGCA; ADL; DAG2; Alpha-sarcoglycan; Alpha-SG; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2

UniProt

Q16586

Swiss Prot

Q16586

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human SGCA. AA range:161-210

Target

Sarcoglycan α

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Buffer

-20°C/1 year

Molecular Weight

43kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

43kD

Fragment

IgG

Subcellular Location

Cell membrane, sarcolemma ; Single-pass type I membrane protein . Cytoplasm, cytoskeleton .

Other Product Names

SGCA; ADL; DAG2; Alpha-sarcoglycan; Alpha-SG; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2

Gene ID (Human)

6442

Available Sizes

Curated Selection

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