Cerebellin 3 rabbit pAb

Members of the precerebellin family, such as CBLN3, contain a cerebellin motif (see CBLN1; MIM 600432) and a C-terminal C1q signature domain (see MIM 120550) that mediates trimeric assembly of atypical collagen complexes. However, precerebellins do not contain a collagen motif, suggesting that they are not conventional components of the extracellular matrix (Pang et al. 2000 [PubMed 10964938]). [supplied by OMIM, Aug 2009],

Product Specifications

Background

Members of the precerebellin family, such as CBLN3, contain a cerebellin motif (see CBLN1; MIM 600432) and a C-terminal C1q signature domain (see MIM 120550) that mediates trimeric assembly of atypical collagen complexes. However, precerebellins do not contain a collagen motif, suggesting that they are not conventional components of the extracellular matrix (Pang et al., 2000 [PubMed 10964938]) .[supplied by OMIM, Aug 2009]

UniProt

Q6UW01

Swiss Prot

Q6UW01

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human CBLN3. AA range:131-180

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

27kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

27kD

Fragment

IgG

Subcellular Location

Endoplasmic reticulum . Golgi apparatus, cis-Golgi network . Secreted . Cell junction, synapse . In the absence of CBLN1, remains in the endoplasmic reticulum/cis-Golgi apparatus. Partial secretion depends on an association with CBLN1 and maybe CBLN4, but not on CBLN2 (By similarity) . .