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Cerebellin 3 rabbit pAb

Members of the precerebellin family, such as CBLN3, contain a cerebellin motif (see CBLN1; MIM 600432) and a C-terminal C1q signature domain (see MIM 120550) that mediates trimeric assembly of atypical collagen complexes. However, precerebellins do not contain a collagen motif, suggesting that they are not conventional components of the extracellular matrix (Pang et al. 2000 [PubMed 10964938]). [supplied by OMIM, Aug 2009],

Product Specifications

Background

Members of the precerebellin family, such as CBLN3, contain a cerebellin motif (see CBLN1; MIM 600432) and a C-terminal C1q signature domain (see MIM 120550) that mediates trimeric assembly of atypical collagen complexes. However, precerebellins do not contain a collagen motif, suggesting that they are not conventional components of the extracellular matrix (Pang et al., 2000 [PubMed 10964938]) .[supplied by OMIM, Aug 2009]

Synonyms

CBLN3; Cerebellin-3

Gene ID

643866

UniProt

Q6UW01

Cellular Locus

Endoplasmic reticulum. Golgi apparatus, cis-Golgi network. Secreted. Cell junction, synapse. In the absence of CBLN1, remains in the endoplasmic reticulum/cis-Golgi apparatus. Partial secretion depends on an association with CBLN1 and maybe CBLN4, but not on CBLN2 (By similarity)..

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human CBLN3. AA range:131-180

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, IF, WB, ELISA

Validated Applications

IHC,IF,WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

27kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7168-1.pdf

Observed Molecular Weight

27 kD

Subcellular Location

Endoplasmic reticulum . Golgi apparatus, cis-Golgi network . Secreted . Cell junction, synapse . In the absence of CBLN1, remains in the endoplasmic reticulum/cis-Golgi apparatus. Partial secretion depends on an association with CBLN1 and maybe CBLN4, but not on CBLN2 (By similarity) . .

Other Product Names

CBLN3; Cerebellin-3

Gene ID (Human)

643866

SwissProt (Human)

Q6UW01

Available Sizes

Curated Selection

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