ETL rabbit pAb
Developmental stage: Up-regulated in the adult heart. Domain: The transmembrane domain is not required for cleavage, but it is required for dimer formation. function: Could be involved in cardiac development. PTM: Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. similarity: Contains 1 GPS domain. similarity: Contains 2 EGF-like domains. subunit: Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Forms stable dimer at the cells surface. tissue specificity: Mainly expressed in smooth muscle.
Product Specifications
Background
UniProt
Q9HBW9
Swiss Prot
Q9HBW9
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human ELTD1. AA range:251-300
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
77kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
77kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein .
Other Product Names
ELTD1; ETL; EGF; latrophilin and seven transmembrane domain-containing protein 1; EGF-TM7-latrophilin-related protein; ETL protein
Gene ID (Human)
64123
Available Sizes
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