Rhotekin rabbit pAb
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q9BST9
Swiss Prot
Q9BST9
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from Rhotekin . at AA range: 80-160
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7109-1.pdf
Fragment
IgG
Subcellular Location
Cytosol
Other Product Names
RTKN; RTKN1; Rhotekin
Gene ID (Human)
6242
Available Sizes
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