GRK 1 (phospho Ser21) rabbit pAb
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
GRK1; RHOK; Rhodopsin kinase; RK; G protein-coupled receptor kinase 1
Gene ID
6011
UniProt
Q15835
Cellular Locus
Membrane ; Lipid-anchor. Cell projection, cilium, photoreceptor outer segment. Subcellular location is not affected by light or dark conditions..
Host
Rabbit
Species Reactivity
Human,Mouse,Rat,Monkey
Reactivity
Human; Mouse; Rat; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human GRK1 around the phosphorylation site of Ser21. AA range:6-55
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
63kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7047-1.pdf
Observed Molecular Weight
63 kD
Subcellular Location
Membrane ; Lipid-anchor . Cell projection, cilium, photoreceptor outer segment . Subcellular location is not affected by light or dark conditions. .
Other Product Names
GRK1; RHOK; Rhodopsin kinase; RK; G protein-coupled receptor kinase 1
Gene ID (Human)
6011
SwissProt (Human)
Q15835
Available Sizes
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