Recoverin rabbit pAb

This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq, Jul 2008],

Product Specifications

Background

UniProt

P35243

Swiss Prot

P35243

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human Recoverin. AA range:107-156

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

23kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

23kD

Fragment

IgG

Subcellular Location

Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment . Photoreceptor outer segment membrane ; Lipid-anchor ; Cytoplasmic side . Perikaryon . Primarily expressed in the inner segments of light-adapted rod photoreceptors, approximately 10% of which translocates from photoreceptor outer segments upon light stimulation (By similarity) . Targeting of myristoylated protein to rod photoreceptor outer segments is calcium dependent (By similarity) . .