What is the catalog number for RARα rabbit pAb?

The catalog number for RARα rabbit pAb is ES6992.

What sizes are available for RARα rabbit pAb?

RARα rabbit pAb is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does RARα rabbit pAb come in?

RARα rabbit pAb is available in 2 different pack sizes.

Is RARα rabbit pAb in stock?

RARα rabbit pAb is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RARα rabbit pAb?

RARα rabbit pAb is manufactured by ELK.

What is the estimated delivery time for RARα rabbit pAb?

Estimated delivery time for RARα rabbit pAb is approximately 10 business day(s), depending on your location.

RARα rabbit pAb

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus. [provided by RefSeq, Sep 2010],

Product Specifications

Background

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]

UniProt

P10276

Swiss Prot

P10276

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Retinoic Acid Receptor alpha. AA range:46-95

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

51kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

51kD

Fragment

IgG

Subcellular Location

Nucleus . Cytoplasm . Nuclear localization depends on ligand binding, phosphorylation and sumoylation (PubMed:19850744) . Translocation to the nucleus in the absence of ligand is dependent on activation of PKC and the downstream MAPK phosphorylation (By similarity) . Increased nuclear localization upon pulsatile shear stress (PubMed:28167758) . .