Brk (phospho Tyr447) rabbit pAb
Protein tyrosine kinase 6 (PTK6) Homo sapiens The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],
Product Specifications
Background
Product Name Alternative
PTK6; BRK; Protein-tyrosine kinase 6; Breast tumor kinase; Tyrosine-protein kinase BRK
UniProt
Q13882
Swiss Prot
Q13882
Reactivity
Human; Rat; Mouse
Immunogen
Target
Brk
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
50kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
50kD
Fragment
IgG
Subcellular Location
Other Product Names
PTK6; BRK; Protein-tyrosine kinase 6; Breast tumor kinase; Tyrosine-protein kinase BRK
Gene ID (Human)
5753
Available Sizes
Frequently Asked Questions
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