Ersentilide

Ersentilide, a benzamide derivative, is a is a β1-adrenoceptor antagonist and Ikr blocker. Ersentilide is effective in several intact animal models of arrhythmia[1][2].

Product Specifications

CAS Number

[125279-79-0]

UNSPSC

12352005

Target

Adrenergic Receptor; Potassium Channel

Type

Reference compound

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ersentilide.html

Smiles

CS(NC(C=C1)=CC=C1OC[C@@H](O)CNCCOC2=CC=C(N3C=CN=C3)C=C2)(=O)=O

Molecular Formula

C21H26N4O5S

Molecular Weight

446.52

References & Citations

[1]Adamson PB, et, al. Antifibrillatory efficacy of ersentilide, a novel beta-adrenergic and Ikr blocker, in conscious dogs with a healed myocardial infarction. Cardiovasc Res. 1998 Oct;40 (1) :56-63.