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VHX rabbit pAb

Catalytic activity: A phosphoprotein + H (2)O = a protein + phosphate. Catalytic activity: Protein tyrosine phosphate + H (2)O = protein tyrosine + phosphate. function: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK). similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. similarity: Contains 1 tyrosine-protein phosphatase domain. tissue specificity: Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.

Product Specifications

Background

Catalytic activity:A phosphoprotein + H (2) O = a protein + phosphate., catalytic activity:Protein tyrosine phosphate + H (2) O = protein tyrosine + phosphate., function:Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) ., similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily., similarity:Contains 1 tyrosine-protein phosphatase domain., tissue specificity:Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.

Synonyms

DUSP22; JSP1; LMWDSP2; MKPX; Dual specificity protein phosphatase 22; JNK-stimulatory phosphatase-1; JSP-1; Low molecular weight dual specificity phosphatase 2; LMW-DSP2; Mitogen-activated protein kinase phosphatase x; MAP kinase phosphatas

Gene ID

56940

UniProt

Q9NRW4

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human DUSP22. AA range:121-170

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

21kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6863-1.pdf

Observed Molecular Weight

21 kD

Subcellular Location

Cytoplasm .

Other Product Names

DUSP22; JSP1; LMWDSP2; MKPX; Dual specificity protein phosphatase 22; JNK-stimulatory phosphatase-1; JSP-1; Low molecular weight dual specificity phosphatase 2; LMW-DSP2; Mitogen-activated protein kinase phosphatase x; MAP kinase phosphatas

Gene ID (Human)

56940

SwissProt (Human)

Q9NRW4

Available Sizes

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