MEK-6 (phospho Ser207) rabbit pAb
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
Gene ID
5608
UniProt
P52564
Cellular Locus
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Binds to microtubules.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human MEK-6 (phospho Ser207)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6830-1.pdf
Subcellular Location
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Binds to microtubules.
Other Product Names
Gene ID (Human)
5608
SwissProt (Human)
P52564
Available Sizes
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