ERK 3 (phospho Ser189) rabbit pAb
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
Gene ID
5597
UniProt
Q16659
Cellular Locus
Cytoplasm. Nucleus. Translocates to the cytoplasm following interaction with MAPKAPK5..
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ERK3 around the phosphorylation site of Ser189. AA range:155-204
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
90kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6816-1.pdf
Observed Molecular Weight
90 kD
Subcellular Location
Cytoplasm . Nucleus . Translocates to the cytoplasm following interaction with MAPKAPK5. .
Other Product Names
Gene ID (Human)
5597
SwissProt (Human)
Q16659
Available Sizes
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