PKD1 (phospho Tyr463) rabbit pAb
PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al. 2009 [PubMed 19329994]). [supplied by OMIM, Nov 2010],
Product Specifications
Background
Synonyms
PRKD1; PKD; PKD1; PRKCM; Serine/threonine-protein kinase D1; Protein kinase C mu type; Protein kinase D; nPKC-D1; nPKC-mu
Gene ID
5587
UniProt
Q15139
Cellular Locus
Cytoplasm. Cell membrane. Golgi apparatus, trans-Golgi network. Translocation to the cell membrane is required for kinase activation.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PKD1/PKC mu around the phosphorylation site of Tyr463. AA range:429-478
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
130kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6787-1.pdf
Observed Molecular Weight
130 kD
Subcellular Location
Cytoplasm . Cell membrane . Golgi apparatus, trans-Golgi network . Translocation to the cell membrane is required for kinase activation.
Other Product Names
PRKD1; PKD; PKD1; PRKCM; Serine/threonine-protein kinase D1; Protein kinase C mu type; Protein kinase D; nPKC-D1; nPKC-mu
Gene ID (Human)
5587
SwissProt (Human)
Q15139
Available Sizes
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