EDEM2 rabbit pAb
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al. 2005 [PubMed 15537790]). [supplied by OMIM, Mar 2008],
Product Specifications
Background
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD) . EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]) .[supplied by OMIM, Mar 2008]
UniProt
Q9BV94
Swiss Prot
Q9BV94
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human EDEM2.
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Endoplasmic reticulum lumen .
Other Product Names
EDEM2; C20orf31; C20orf49; ER degradation-enhancing alpha-mannosidase-like 2
Gene ID (Human)
55741
Available Sizes
Curated Selection
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