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Sox-6 rabbit pAb

SRY-box 6 (SOX6) Homo sapiens This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009],

Product Specifications

Background

SRY-box 6 (SOX6) Homo sapiens This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

UniProt

P35712

Swiss Prot

P35712

Reactivity

Human; Mouse; Rat; Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human SOX6. AA range:10-59

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight

91kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

91kD

Fragment

IgG

Subcellular Location

Nucleus . Cytoplasm .

Other Product Names

SOX6; Transcription factor SOX-6

Gene ID (Human)

55553

Available Sizes

Curated Selection

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