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Epsin 3 rabbit pAb

Induction: In keratinocytes, by wounding or contact with collagen. similarity: Belongs to the epsin family. similarity: Contains 1 ENTH (epsin N-terminal homology) domain. similarity: Contains 2 UIM (ubiquitin-interacting motif) repeats. subcellular location: Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus. tissue specificity: Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.

Product Specifications

Background

Induction:In keratinocytes, by wounding or contact with collagen., similarity:Belongs to the epsin family., similarity:Contains 1 ENTH (epsin N-terminal homology) domain., similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats., subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus., tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.

UniProt

Q9H201

Swiss Prot

Q9H201

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human EPN3. AA range:401-450

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

68kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

68kD

Fragment

IgG

Subcellular Location

Cytoplasm . Cytoplasm, perinuclear region . Cytoplasmic vesicle, clathrin-coated vesicle . Nucleus . Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.

Other Product Names

EPN3; Epsin-3; EPS-15-interacting protein 3

Gene ID (Human)

55040

Available Sizes

Curated Selection

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