DUS2L rabbit pAb

Dihydrouridine synthase 2 (DUS2) Homo sapiens This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012],

Product Specifications

Background

UniProt

Q9NX74

Swiss Prot

Q9NX74

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human DUS2L. AA range:421-470

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

55kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

55kD

Fragment

IgG

Subcellular Location

Cytoplasm . Endoplasmic reticulum . Mainly at the endoplasmic reticulum. .

Other Product Names

DUS2L; DUS2; tRNA-dihydrouridine (20) synthase [NAD (P) +]-like; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2