FEV rabbit pAb
This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
FEV; PET1; Protein FEV; Fifth Ewing variant protein; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; Pet-1
UniProt
Q99581
Swiss Prot
Q99581
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human FEV.
Target
FEV
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
25kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
25kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
FEV; PET1; Protein FEV; Fifth Ewing variant protein; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; Pet-1
Gene ID (Human)
54738
Available Sizes
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