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GPR85 rabbit pAb

Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al. 2000 [PubMed 10833454]). [supplied by OMIM, Aug 2008],

Product Specifications

Background

Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]) .[supplied by OMIM, Aug 2008]

Synonyms

GPR85; SREB2; Probable G-protein coupled receptor 85; Super conserved receptor expressed in brain 2

Gene ID

54329

UniProt

P60893

Cellular Locus

Cell membrane ; Multi-pass membrane protein. Endoplasmic reticulum.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human GPR85. AA range:181-230

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, IF, ELISA

Validated Applications

IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES6648-1.pdf

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum .

Other Product Names

GPR85; SREB2; Probable G-protein coupled receptor 85; Super conserved receptor expressed in brain 2

Gene ID (Human)

54329

SwissProt (Human)

P60893

Available Sizes

Curated Selection

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